[4] East Carolina 25-27 Cincinnati [3] 2022-11-12 01:00
Stadium: Nippert Stadium Round: 1
Home Manager: Luke Fickell Away Manager: Mike Houston
Head to Head
| NCAAF | 2021/11/26 20:30 | Cincinnati v East Carolina | L | 35-13 |
| NCAAF | 2020/11/14 00:30 | East Carolina v Cincinnati | L | 17-55 |
| NCAAF | 2019/11/02 23:00 | Cincinnati v East Carolina | L | 46-43 |
| NCAAF | 2018/11/23 20:30 | East Carolina v Cincinnati | L | 6-56 |
| NCAAF | 2017/11/18 17:00 | Cincinnati v East Carolina | W | 20-48 |
| NCAAF | 2016/10/22 23:00 | East Carolina v Cincinnati | L | 19-31 |
| NCAAF | 2015/11/28 17:00 | East Carolina v Cincinnati | L | 16-19 |
| NCAAF | 2014/11/14 00:00 | Cincinnati v East Carolina | L | 54-46 |
| NCAAF | 2004/09/25 12:00 | East Carolina v Cincinnati | L | 19-24 |
| NCAAF | 2003/09/01 12:00 | Cincinnati v East Carolina | L | 40-3 |
| NCAAF | 2002/12/06 12:00 | East Carolina v Cincinnati | L | 26-42 |
| NCAAF | 2001/11/10 12:00 | Cincinnati v East Carolina | W | 26-28 |