[2] Santos Laguna 1-2 Unam Pumas [10] 2018-04-22 23:00
Weer: Goed Stadium: Estadio TSM Corona Veld: Goed Round: 16
Referee: Jorge Isaac Rojas Castillo Home Manager: Robert Siboldi Away Manager: David Patino Oviedo
Head to Head
| Mexico - Liga MX | 2017/11/05 18:00 | Unam Pumas v Santos Laguna | D | 2-2 |
| Mexico - Liga MX | 2017/03/05 18:00 | Unam Pumas v Santos Laguna | L | 2-1 |
| Mexico - Liga MX | 2016/09/18 23:00 | Santos Laguna v Unam Pumas | W | 3-1 |
| Wereld - Vriendschappelijke clubwedstrijden | 2016/07/02 23:00 | Unam Pumas v Santos Laguna | W | 1-2 |
| Mexico - Liga MX | 2016/02/21 18:00 | Unam Pumas v Santos Laguna | D | 1-1 |
| Mexico - Liga MX | 2015/08/29 02:30 | Santos Laguna v Unam Pumas | L | 3-4 |
| Mexico - Liga MX | 2015/04/19 17:00 | Unam Pumas v Santos Laguna | L | 1-0 |
| Mexico - Liga MX | 2014/10/25 02:30 | Santos Laguna v Unam Pumas | D | 1-1 |
Home History
| Mexico - Liga MX | 2018/04/15 00:06 | Pachuca v Santos Laguna | L | 3-1 |
| Mexico - Liga MX | 2018/04/08 23:00 | Santos Laguna v Queretaro | W | 3-0 |
| Mexico - Beker | 2018/04/05 02:15 | Necaxa v Santos Laguna | L | 2-1 |
| Mexico - Liga MX | 2018/03/31 03:00 | Atlas v Santos Laguna | L | 3-2 |
| Mexico - Liga MX | 2018/03/17 01:00 | Puebla v Santos Laguna | W | 0-1 |
| Mexico - Beker | 2018/03/14 03:15 | Santos Laguna v Queretaro | W | 1-0 |
| Mexico - Liga MX | 2018/03/12 00:00 | Santos Laguna v Monterrey | W | 3-2 |
| Mexico - Beker | 2018/03/07 03:05 | Tampico Madero v Santos Laguna | W | 0-1 |
Away History
| Mexico - Liga MX | 2018/04/15 17:00 | Unam Pumas v Puebla | W | 4-2 |
| Mexico - Liga MX | 2018/04/08 00:00 | Monterrey v Unam Pumas | L | 2-1 |
| Mexico - Liga MX | 2018/04/01 17:00 | Unam Pumas v Necaxa | D | 1-1 |
| Mexico - Liga MX | 2018/03/17 23:00 | Cruz Azul v Unam Pumas | D | 1-1 |
| Mexico - Beker | 2018/03/15 03:15 | Unam Pumas v Necaxa | L | 1-2 |
| Mexico - Liga MX | 2018/03/11 18:00 | Unam Pumas v Toluca | L | 0-1 |
| Mexico - Beker | 2018/03/08 03:05 | Unam Pumas v Lobos BUAP | W | 3-0 |
| Mexico - Liga MX | 2018/03/04 01:06 | Leon v Unam Pumas | L | 3-0 |