| NCAAB | 03/08 02:30 | 122 | [11] Illinois Chicago v Southern Illinois [5] | L | 84-82 | |
| NCAAB | 03/03 19:00 | - | [6] Northern Iowa v Southern Illinois [4] | L | 82-70 | |
| NCAAB | 02/29 01:00 | - | [4] Southern Illinois v Bradley [3] | L | 67-86 | |
| NCAAB | 02/25 19:00 | - | [4] Southern Illinois v Evansville [7] | W | 65-53 | |
| NCAAB | 02/22 01:00 | - | [10] Murray State v Southern Illinois [4] | W | 68-72 | |
| NCAAB | 02/18 00:00 | - | [1] Indiana State v Southern Illinois [4] | W | 69-74 | |
| NCAAB | 02/15 00:30 | - | [4] Southern Illinois v Belmont [6] | L | 68-82 | |
| NCAAB | 02/11 00:00 | - | [9] Illinois State v Southern Illinois [4] | W | 66-69 | |
| NCAAB | 02/08 01:00 | - | [4] Southern Illinois v Drake [2] | L | 88-92 | |
| NCAAB | 02/03 19:00 | - | [4] Southern Illinois v Illinois Chicago [11] | W | 74-71 | |
| NCAAB | 02/01 01:00 | - | [7] Missouri State v Southern Illinois [4] | L | 76-75 | |
| NCAAB | 01/27 19:00 | - | [4] Southern Illinois v Murray State [10] | W | 60-58 | |
| NCAAB | 01/25 01:00 | - | [12] Valparaiso v Southern Illinois [4] | W | 69-75 | |
| NCAAB | 01/21 01:00 | - | [4] Southern Illinois v Northern Iowa [7] | L | 57-61 | |
| NCAAB | 01/18 01:00 | - | [4] Bradley v Southern Illinois [3] | L | 70-69 | |
| NCAAB | 01/14 01:00 | - | [2] Drake v Southern Illinois [3] | L | 76-58 | |
| NCAAB | 01/11 01:00 | - | [3] Southern Illinois v Valparaiso [12] | W | 77-68 | |
| NCAAB | 01/07 00:00 | - | [3] Southern Illinois v Illinois State [8] | W | 71-64 | |
| NCAAB | 01/03 01:00 | - | [4] Belmont v Southern Illinois [5] | W | 63-73 | |
| NCAAB | 12/31 00:00 | - | [9] Illinois Chicago v Southern Illinois [6] | W | 50-62 | |
| NCAAB | 12/23 00:00 | - | [1] Southern Indiana v Southern Illinois [7] | W | 50-81 | |
| NCAAB | 12/20 01:00 | - | [1] North Dakota State v Southern Illinois [8] | W | 63-76 | |
| NCAAB | 12/17 00:00 | - |
[5] Southern Illinois
v
Wichita State
[1] 
|
L | 68-69 | |
| NCAAB | 12/13 01:00 | - | [1] Austin Peay v Southern Illinois [4] | L | 70-68 | |
| NCAAB | 12/06 02:00 | - |
[1] Oklahoma State
v
Southern Illinois
[6] |
W | 68-70 | |
| NCAAB | 12/02 20:30 | - | [1] Saint Louis v Southern Illinois [6] | W | 62-101 | |
| NCAAB | 11/29 00:00 | - | Southern Illinois v Indiana State | L | 48-77 | |
| NCAAB | 11/22 23:00 | - | Southern Illinois v New Mexico State | W | 81-54 | |
| NCAAB | 11/21 23:00 | - | James Madison v Southern Illinois | L | 82-76 | |
| NCAAB | 11/17 01:00 | - | Chicago State v Southern Illinois | W | 55-71 |
Southern Illinois Salukis is een dames- en herenbasketbalteam aan de Southern Illinois University in Carbondale, Illinois, Verenigde Staten. De teams strijden in de NCAA Division I en spelen hun thuiswedstrijden in het Banterra Center. Het mannenbasketbalteam is vooral bekend om zijn succesvolle runs in het NCAA Tournament, met deelnames aan de Sweet Sixteen in 2002, 2004, 2005, 2007 en 2022. Het vrouwenbasketbalteam is elf keer verschenen in het NCAA Tournament, met deelnames aan de Elite Eight in 2007.