[8] Guairena FC 0-1 Guarani Asuncion [5] 2020-12-28 00:00
Stadium: Estadio Parque del Guaira Round: 2
Referee: Mario Alberto Diaz De Vivar Home Manager: Troadio Daniel Duarte Away Manager: Gustavo Costas
Head to Head
| Paraguay - División Profesional | 2020/12/19 22:30 | Guarani Asuncion v Guairena FC | L | 1-0 |
| Paraguay - División Profesional | 2020/09/20 21:00 | Guarani Asuncion v Guairena FC | D | 0-0 |
| Paraguay - División Profesional | 2020/07/23 22:00 | Guairena FC v Guarani Asuncion | D | 1-1 |