[4] Lokomotiv Moskou 0-1 FC Schalke 04 [3] 2018-10-03 16:55
Stadium: RZD Arena Round: 2
Referee: Anthony Taylor Home Manager: Yury Semin Away Manager: Domenico Tedesco
Home History
| Rusland - Premier League | 2018/09/29 16:00 | Lokomotiv Moskou v FC Akhmat Grozny | W | 2-0 |
| Rusland - Beker | 2018/09/26 18:00 | Baltika Kaliningrad v Lokomotiv Moskou | W | 2-3 |
| Rusland - Premier League | 2018/09/23 13:30 | Zenit St Petersburg v Lokomotiv Moskou | L | 5-3 |
| UEFA Champions League | 2018/09/18 19:00 | Galatasaray SK v Lokomotiv Moskou | L | 3-0 |
| Rusland - Premier League | 2018/09/14 16:30 | Lokomotiv Moskou v Dinamo Moskou | D | 1-1 |
| Rusland - Premier League | 2018/09/01 16:00 | Krasnodar v Lokomotiv Moskou | L | 2-1 |
| Rusland - Premier League | 2018/08/26 16:00 | Lokomotiv Moskou v Anzhi Makhachkala | W | 2-1 |
| Rusland - Premier League | 2018/08/19 13:30 | Krylia Sovetov v Lokomotiv Moskou | W | 0-1 |
Away History
| Duitsland - Bundesliga | 2018/09/29 13:30 | FC Schalke 04 v Mainz | W | 1-0 |
| Duitsland - Bundesliga | 2018/09/25 18:30 | SC Freiburg v FC Schalke 04 | L | 1-0 |
| Duitsland - Bundesliga | 2018/09/22 16:30 | FC Schalke 04 v Bayern München | L | 0-2 |
| UEFA Champions League | 2018/09/18 19:00 | FC Schalke 04 v FC Porto | D | 1-1 |
| Duitsland - Bundesliga | 2018/09/15 16:30 | Borussia M'gladbach v FC Schalke 04 | L | 2-1 |
| Duitsland - Bundesliga | 2018/09/02 16:00 | FC Schalke 04 v Hertha Berlin | L | 0-2 |
| Duitsland - Bundesliga | 2018/08/25 13:30 | Wolfsburg v FC Schalke 04 | L | 2-1 |
| Duitsland - DFB Pokal | 2018/08/17 18:45 | Schweinfurt 05 v FC Schalke 04 | W | 0-2 |