Stadium: Panther Stadium at Blackshear Field Round: 1
Home Manager: Bubba McDowell Away Manager: Kendrick Wade
| NCAAF | 2022/11/19 19:00 | Prairie View v Mississippi Valley State | W | 7-27 |
| NCAAF | 2021/11/27 20:00 | Mississippi Valley State v Prairie View | W | 24-19 |
| NCAAF | 2023/09/30 23:00 | Florida A&M v Mississippi Valley State | L | 31-7 |
| NCAAF | 2023/09/23 19:00 | Mississippi Valley State v North Carolina Central | L | 3-45 |
| NCAAF | 2023/09/16 23:00 | Delta State v Mississippi Valley State | L | 35-7 |
| NCAAF | 2023/09/02 20:00 | Mississippi Valley State v Central State | L | 21-24 |
| NCAAF | 2022/11/19 19:00 | Prairie View v Mississippi Valley State | W | 7-27 |
| NCAAF | 2022/11/12 20:00 | Southern v Mississippi Valley State | L | 27-7 |
| NCAAF | 2022/11/03 23:30 | Alabama v Mississippi Valley State | W | 20-30 |
| NCAAF | 2022/10/22 20:00 | Bethune Cookman v Mississippi Valley State | L | 45-35 |
| NCAAF | 2023/09/30 23:00 | Grambling State v Prairie View | L | 35-20 |
| NCAAF | 2023/09/23 23:00 | Prairie View v Alcorn State | W | 23-20 |
| NCAAF | 2023/09/16 23:00 | Prairie View v SMU | L | 0-69 |
| NCAAF | 2023/09/09 23:00 | Abilene Christian v Prairie View | L | 45-16 |
| NCAAF | 2023/09/03 00:00 | Prairie View v Texas Southern Tigers | W | 37-34 |
| NCAAF | 2022/11/19 19:00 | Prairie View v Mississippi Valley State | L | 7-27 |
| NCAAF | 2022/11/12 20:00 | Prairie View v Arkansas Pine Bluff | W | 55-24 |
| NCAAF | 2022/11/04 23:30 | Alcorn State v Prairie View | L | 23-16 |