| Uruguay - Reserve League | 2022/12/05 13:00 | Deportivo Maldonado - Reserves v Defensor Sporting - Reserves | L | 2-1 |
| Uruguay - Reserve League | 2022/06/06 18:00 | Defensor Sporting - Reserves v Deportivo Maldonado - Reserves | D | 1-1 |
| Uruguay - Reserve League | 2023/04/17 12:30 | Boston River - Reserves v Defensor Sporting - Reserves | D | 1-1 |
| Uruguay - Reserve League | 2023/04/12 12:00 | Defensor Sporting - Reserves v CA Cerro - Reserves | W | 2-1 |
| Uruguay - Reserve League | 2023/04/03 12:00 | Racing Club de Montevideo - Reserves v Defensor Sporting - Reserves | W | 0-4 |
| Uruguay - Reserve League | 2023/03/27 13:30 | Defensor Sporting - Reserves v Plaza Colonia - Reserves | W | 2-1 |
| Uruguay - Reserve League | 2023/03/14 12:00 | Defensor Sporting - Reserves v Liverpool Montevideo - Reserves | W | 3-0 |
| Uruguay - Reserve League | 2023/03/06 20:00 | Torque - Reserves v Defensor Sporting - Reserves | L | 2-1 |
| Uruguay - Reserve League | 2023/02/26 11:30 | Defensor Sporting - Reserves v Penarol - Reserves | L | 1-3 |
| Uruguay - Reserve League | 2022/12/08 19:00 | Defensor Sporting - Reserves v Rentistas - Reserves | D | 1-1 |
| Uruguay - Reserve League | 2023/04/18 13:30 | Deportivo Maldonado - Reserves v La Luz - Reserves | D | 0-0 |
| Uruguay - Reserve League | 2023/04/10 18:30 | Montevideo Wanderers - Reserves v Deportivo Maldonado - Reserves | L | 4-0 |
| Uruguay - Reserve League | 2023/04/03 19:00 | Deportivo Maldonado - Reserves v Atletico Fenix - Reserves | L | 0-1 |
| Uruguay - Reserve League | 2023/03/27 13:30 | Danubio - Reserves v Deportivo Maldonado - Reserves | D | 1-1 |
| Uruguay - Reserve League | 2023/03/22 19:30 | Deportivo Maldonado - Reserves v Nacional de Montevideo - Reserves | W | 3-2 |
| Uruguay - Reserve League | 2023/03/14 20:00 | Atletico River Plate Reserves v Deportivo Maldonado - Reserves | D | 2-2 |
| Uruguay - Reserve League | 2023/03/06 13:00 | Penarol - Reserves v Deportivo Maldonado - Reserves | D | 0-0 |
| Uruguay - Reserve League | 2023/02/27 13:00 | Deportivo Maldonado - Reserves v Boston River - Reserves | W | 1-0 |