[8] South Florida 24-28 Cincinnati [3] 2022-10-08 18:30
Stadium: Nippert Stadium Round: 1
Home Manager: Luke Fickell Away Manager: Jeff Scott
Head to Head
| NCAAF | 2021/11/12 23:00 | Cincinnati v South Florida | L | 45-28 |
| NCAAF | 2020/10/03 19:30 | South Florida v Cincinnati | L | 7-28 |
| NCAAF | 2019/11/17 00:00 | Cincinnati v South Florida | L | 20-17 |
| NCAAF | 2018/11/11 00:00 | South Florida v Cincinnati | L | 23-35 |
| NCAAF | 2017/10/14 23:30 | Cincinnati v South Florida | W | 3-33 |
| NCAAF | 2016/10/01 23:00 | South Florida v Cincinnati | W | 45-20 |
| NCAAF | 2015/11/21 01:00 | South Florida v Cincinnati | W | 65-27 |
| NCAAF | 2014/10/24 23:00 | Cincinnati v South Florida | L | 34-17 |
Home History
| NCAAF | 2022/10/01 18:30 | East Carolina v South Florida | L | 48-28 |
| NCAAF | 2022/09/24 16:00 | South Florida v Louisville | L | 3-41 |
| NCAAF | 2022/09/17 23:30 | South Florida v Florida | L | 28-31 |
| NCAAF | 2022/09/10 23:00 | Howard v South Florida | W | 20-42 |
| NCAAF | 2022/09/03 20:00 | BYU v South Florida | L | 50-21 |
| NCAAF | 2021/11/26 20:30 | South Florida v Central Florida | L | 13-17 |
| NCAAF | 2021/11/20 17:00 | South Florida v Tulane | L | 14-45 |
| NCAAF | 2021/11/12 23:00 | Cincinnati v South Florida | L | 45-28 |
Away History
| NCAAF | 2022/10/01 23:00 | Cincinnati v Tulsa | W | 31-21 |
| NCAAF | 2022/09/24 19:30 | Indiana v Cincinnati | W | 24-45 |
| NCAAF | 2022/09/17 16:00 | Cincinnati v Miami Ohio | W | 38-17 |
| NCAAF | 2022/09/10 19:30 | Kennesaw State v Cincinnati | W | 10-63 |
| NCAAF | 2022/09/03 19:30 | Cincinnati v Arkansas | L | 24-31 |
| NCAAF | 2021/12/31 20:30 | Cincinnati v Alabama | L | 6-27 |
| NCAAF | 2021/12/04 21:00 | Houston v Cincinnati | W | 20-35 |
| NCAAF | 2021/11/26 20:30 | Cincinnati v East Carolina | W | 35-13 |