| Uruguay - Reserve League | 2021/10/04 18:30 | Rentistas - Reserves v Atletico River Plate Reserves | D | 2-2 |
| Uruguay - Reserve League | 2022/05/18 13:00 | Deportivo Maldonado - Reserves v Atletico River Plate Reserves | L | 2-1 |
| Uruguay - Reserve League | 2022/05/09 18:00 | Atletico River Plate Reserves v Danubio - Reserves | W | 2-1 |
| Uruguay - Reserve League | 2022/05/05 18:00 | Atletico River Plate Reserves v Montevideo Wanderers - Reserves | W | 2-1 |
| Uruguay - Reserve League | 2022/05/02 18:00 | Nacional de Montevideo - Reserves v Atletico River Plate Reserves | D | 2-2 |
| Uruguay - Reserve League | 2022/04/05 19:00 | Defensor Sporting - Reserves v Atletico River Plate Reserves | W | 0-2 |
| Uruguay - Reserve League | 2022/03/28 19:00 | Atletico River Plate Reserves v Atletico Fenix - Reserves | L | 0-5 |
| Uruguay - Reserve League | 2022/03/15 13:30 | Atletico River Plate Reserves v Cerrito - Reserves | W | 3-0 |
| Uruguay - Reserve League | 2022/03/01 13:30 | Atletico River Plate Reserves v Boston River - Reserves | W | 4-0 |
| Uruguay - Reserve League | 2022/05/19 18:00 | Rentistas - Reserves v Boston River - Reserves | W | 3-2 |
| Uruguay - Reserve League | 2022/05/10 13:30 | Plaza Colonia - Reserves v Rentistas - Reserves | W | 1-2 |
| Uruguay - Reserve League | 2022/05/02 18:00 | Rentistas - Reserves v Montevideo Wanderers - Reserves | L | 0-1 |
| Uruguay - Reserve League | 2022/04/05 19:00 | Rentistas - Reserves v Penarol - Reserves | D | 1-1 |
| Uruguay - Reserve League | 2022/03/28 19:00 | Liverpool Montevideo - Reserves v Rentistas - Reserves | L | 3-2 |
| Uruguay - Reserve League | 2022/03/21 19:00 | Cerrito - Reserves v Rentistas - Reserves | D | 2-2 |
| Uruguay - Reserve League | 2022/03/15 19:30 | Rentistas - Reserves v Deportivo Maldonado - Reserves | W | 1-0 |
| Uruguay - Reserve League | 2022/02/28 19:30 | Danubio - Reserves v Rentistas - Reserves | L | 3-0 |