[14] Diego Schwartzman 5-7,3-6 John Isner [23] 2022-03-15 22:05
Stadium: Stadium 1 Round: 25 Ground: Hardcourt outdoor
Head to Head
| ATP - Parijs | 2017/11/01 10:00 | John Isner v Diego Schwartzman | 7-6,6-7,6-3 |
Home History
| ATP - Indian Wells | 2022/03/13 21:10 | Diego Schwartzman v Emil Ruusuvuori | 5-7,6-3,6-3 |
| Davis Cup | 2022/03/04 16:50 | Diego Schwartzman v Tomas Machac | 2-6,6-2,6-3 |
| ATP - Rio de Janeiro | 2022/02/20 20:30 | Carlos Alcaraz Garfia v Diego Schwartzman | 6-4,6-2 |
| ATP - Rio de Janeiro | 2022/02/19 23:10 | Diego Schwartzman v Francisco Cerundolo | 7-6,6-3 |
| ATP - Rio de Janeiro | 2022/02/19 15:00 | Pablo Andujar v Diego Schwartzman | 6-7,6-4,4-6 |
| ATP - Rio de Janeiro | 2022/02/17 02:15 | Pedro Martinez v Diego Schwartzman | 1-6,1-6 |
| ATP - Buenos Aires | 2022/02/13 19:00 | Casper Ruud v Diego Schwartzman | 5-7,6-2,6-3 |
| ATP - Buenos Aires | 2022/02/12 21:00 | Lorenzo Sonego v Diego Schwartzman | 5-7,6-3,2-6 |
Away History
| ATP - Indian Wells | 2022/03/13 18:00 | Sam Querrey v John Isner | 6-7,6-7 |
| ATP - Acapulco | 2022/02/24 00:00 | Cameron Norrie v John Isner | 6-7,6-3,6-4 |
| ATP - Acapulco | 2022/02/22 00:00 | Fernando Verdasco v John Isner | 5-7,7-6,6-7 |
| ATP - Dallas | 2022/02/12 22:00 | John Isner v Reilly Opelka | 6-7,6-7 |
| ATP - Dallas | 2022/02/12 01:00 | Vasek Pospisil v John Isner | 4-6,4-6 |
| ATP - Dallas | 2022/02/10 01:00 | Kevin Anderson v John Isner | 6-7,7-6,6-7 |
| Australian Open | 2022/01/18 03:15 | Maxime Cressy v John Isner | 7-6,7-5,6-7,6-7,6-4 |
| ATP - Adelaide 2 | 2022/01/12 04:30 | Thanasi Kokkinakis v John Isner | 6-7,7-6,7-6 |