| El Salvador - Reserve league | 2021/08/25 18:00 | CD Platense Zacatecoluca - Reserves v AD Isidro Metapan - Reserves | L | 2-0 |
| El Salvador - Reserve league | 2021/10/31 20:30 | Municipal Limeno - Reserves v AD Isidro Metapan - Reserves | D | 1-1 |
| El Salvador - Reserve league | 2021/10/20 21:30 | CD Aguila - Reserves v AD Isidro Metapan - Reserves | L | 2-1 |
| El Salvador - Reserve league | 2021/10/15 21:00 | AD Isidro Metapan - Reserves v Santa Tecla Reserves | D | 0-0 |
| El Salvador - Reserve league | 2021/10/01 19:45 | Atletico Marte - Reserves v AD Isidro Metapan - Reserves | D | 3-3 |
| El Salvador - Reserve league | 2021/09/26 21:00 | AD Isidro Metapan - Reserves v AD Chalatenago - Reserves | W | 2-0 |
| El Salvador - Reserve league | 2021/09/18 16:00 | CD FAS - Reserves v AD Isidro Metapan - Reserves | D | 2-2 |
| El Salvador - Reserve league | 2021/09/16 21:00 | AD Isidro Metapan - Reserves v Once Deportivo de Ahuachapán - Reserves | D | 2-2 |
| El Salvador - Reserve league | 2021/09/10 19:00 | CD Luis Angel Firpo - Reserves v AD Isidro Metapan - Reserves | W | 2-3 |
| El Salvador - Reserve league | 2021/10/30 17:00 | CD Platense Zacatecoluca - Reserves v CD FAS - Reserves | D | 1-1 |
| El Salvador - Reserve league | 2021/10/24 17:00 | Once Deportivo de Ahuachapán - Reserves v CD Platense Zacatecoluca - Reserves | W | 2-3 |
| El Salvador - Reserve league | 2021/10/17 18:30 | Alianza FC San Salvador - Reserves v CD Platense Zacatecoluca - Reserves | L | 5-0 |
| El Salvador - Reserve league | 2021/10/09 17:00 | CD Platense Zacatecoluca - Reserves v CD Luis Angel Firpo - Reserves | D | 3-3 |
| El Salvador - Reserve league | 2021/10/03 20:30 | CD Platense Zacatecoluca - Reserves v AD Chalatenago - Reserves | D | 0-0 |
| El Salvador - Reserve league | 2021/09/25 21:00 | Municipal Limeno - Reserves v CD Platense Zacatecoluca - Reserves | L | 1-0 |
| El Salvador - Reserve league | 2021/09/19 17:00 | CD Platense Zacatecoluca - Reserves v Jocoro FC - Reserves | D | 0-0 |
| El Salvador - Reserve league | 2021/09/15 21:30 | CD Aguila - Reserves v CD Platense Zacatecoluca - Reserves | L | 3-1 |