[109] Feliciano Lopez 5-7,6-7 Alexei Popyrin [75] 2021-10-23 13:00
Stadium: Center Court Round: 14 Ground: Hardcourt indoor
Head to Head
| ATP - Stuttgart | 2021/06/09 17:10 | Feliciano Lopez v Alexei Popyrin | 6-4,6-4 |
| ATP - Miami | 2021/03/24 15:00 | Feliciano Lopez v Alexei Popyrin | 4-6,6-7 |
Home History
| Challenger - Alicante | 2021/10/14 15:00 | Feliciano Lopez v Hugo Grenier | 3-6,5-7 |
| Challenger - Alicante | 2021/10/12 13:30 | Feliciano Lopez v Roberto Marcora | 6-3,6-1 |
| ATP - Indian Wells | 2021/10/07 19:20 | Tommy Paul v Feliciano Lopez | 6-3,7-6 |
| US Open | 2021/08/30 15:00 | Feliciano Lopez v Bernabe Zapata Miralles | 7-5,6-7,6-4,3-6,3-6 |
| ATP - Winston Salem | 2021/08/23 22:00 | Lucas Pouille v Feliciano Lopez | 6-1,6-4 |
| ATP - Toronto | 2021/08/11 15:00 | Lloyd Harris v Feliciano Lopez | 6-2,6-3 |
| ATP - Toronto | 2021/08/08 17:35 | Yoshihito Nishioka v Feliciano Lopez | 7-5,7-6 |
| ATP - Toronto | 2021/08/07 20:35 | Maxime Cressy v Feliciano Lopez | 6-7,4-6 |
Away History
| ATP - Antwerpen | 2021/10/18 18:00 | Alexei Popyrin v Botic Van De Zandschulp | 4-6,6-3,0-6 |
| ATP - Indian Wells | 2021/10/09 18:00 | Alexei Popyrin v Hubert Hurkacz | 1-6,5-7 |
| ATP - Indian Wells | 2021/10/07 18:00 | Alexei Popyrin v Miomir Kecmanovic | 6-3,7-6 |
| US Open | 2021/09/03 16:55 | Alexei Popyrin v Daniel Evans | 6-4,6-3,3-6,4-6,6-7 |
| US Open | 2021/08/30 21:45 | Alexei Popyrin v Radu Albot | 6-3,6-7,6-3,6-3 |
| ATP - Winston Salem | 2021/08/25 01:25 | Carlos Alcaraz Garfia v Alexei Popyrin | 6-7,6-1,7-6 |
| ATP - Winston Salem | 2021/08/23 23:35 | Steve Johnson v Alexei Popyrin | 5-7,4-6 |
| ATP - Winston Salem | 2021/08/22 18:00 | Alexei Popyrin v Yosuke Watanuki | 6-2,4-6,6-1 |