[18] Willem II 2-0 Heracles Almelo [13] 2022-05-07 18:00
Stadium: Willem II Stadion Round: 32
Referee: Allard Lindhout Home Manager: Kevin Hofland Away Manager: Frank Wormuth
Head to Head
| Nederland - Eredivisie | 2021/10/02 18:00 | Heracles Almelo v Willem II | L | 3-2 |
| Nederland - Eredivisie | 2021/04/10 16:45 | Heracles Almelo v Willem II | L | 4-0 |
| Nederland - Eredivisie | 2020/09/20 12:30 | Willem II v Heracles Almelo | W | 4-0 |
| Nederland - Eredivisie | 2020/02/02 11:15 | Willem II v Heracles Almelo | W | 1-0 |
| Nederland - Eredivisie | 2019/09/15 12:30 | Heracles Almelo v Willem II | L | 4-1 |
| Nederland - Eredivisie | 2019/04/02 17:45 | Heracles Almelo v Willem II | W | 3-4 |
| Nederland - Eredivisie | 2018/08/26 10:15 | Willem II v Heracles Almelo | W | 5-0 |
| Nederland - Eredivisie | 2018/02/10 17:30 | Heracles Almelo v Willem II | L | 1-0 |
Home History
| Nederland - Eredivisie | 2022/05/01 12:30 | PSV v Willem II | L | 4-2 |
| Nederland - Eredivisie | 2022/04/24 10:15 | Willem II v Vitesse | W | 1-0 |
| Nederland - Eredivisie | 2022/04/08 18:00 | Go Ahead Eagles v Willem II | L | 4-0 |
| Nederland - Eredivisie | 2022/04/02 19:00 | Feyenoord v Willem II | L | 2-0 |
| Nederland - Eredivisie | 2022/03/20 19:00 | Willem II v AZ | D | 2-2 |
| Nederland - Eredivisie | 2022/03/13 11:15 | Fortuna Sittard v Willem II | L | 1-0 |
| Nederland - Eredivisie | 2022/03/05 15:30 | Willem II v sc Heerenveen | D | 0-0 |
| Nederland - Eredivisie | 2022/02/26 17:45 | FC Groningen v Willem II | L | 1-0 |
Away History
| Nederland - Eredivisie | 2022/04/30 18:00 | Heracles Almelo v FC Twente | D | 1-1 |
| Nederland - Eredivisie | 2022/04/24 12:30 | FC Groningen v Heracles Almelo | W | 0-1 |
| Nederland - Eredivisie | 2022/04/10 14:45 | Heracles Almelo v Feyenoord | L | 1-4 |
| Nederland - Eredivisie | 2022/04/03 12:30 | Fortuna Sittard v Heracles Almelo | W | 0-2 |
| Europa - Vriendschappelijke wedstrijden | 2022/03/25 12:00 | Bochum v Heracles Almelo | L | 2-0 |
| Nederland - Eredivisie | 2022/03/18 19:00 | sc Heerenveen v Heracles Almelo | L | 2-0 |
| Nederland - Eredivisie | 2022/03/13 13:30 | Heracles Almelo v Vitesse | D | 0-0 |
| Nederland - Eredivisie | 2022/03/06 11:15 | PSV v Heracles Almelo | L | 3-1 |