[78] Troy 14-23 South Carolina [71] 2021-10-02 19:30
Stadium: Williams-Brice Stadium Round: 1
Home Manager: Shane Beamer Away Manager: Chip Lindsey
Head to Head
| NCAAF | 2010/11/20 12:00 | South Carolina v Troy | L | 69-24 |
| NCAAF | 2005/09/24 12:00 | South Carolina v Troy | L | 45-20 |
| NCAAF | 2004/09/25 12:00 | South Carolina v Troy | L | 17-7 |
Home History
| NCAAF | 2021/09/26 00:00 | Troy v UL Monroe | L | 16-29 |
| NCAAF | 2021/09/18 23:00 | Troy v Southern Mississippi | W | 21-9 |
| NCAAF | 2021/09/11 23:00 | Liberty v Troy | L | 21-13 |
| NCAAF | 2021/09/04 23:00 | Southern v Troy | W | 3-55 |
| NCAAF | 2020/12/12 20:00 | Coastal Carolina v Troy | L | 42-38 |
| NCAAF | 2020/12/05 19:00 | Troy v South Alabama | W | 29-0 |
| NCAAF | 2020/11/28 20:30 | Troy v Appalachian St | L | 10-47 |
| NCAAF | 2020/11/21 20:30 | Middle Tennessee St. v Troy | L | 20-17 |
Away History
| NCAAF | 2021/09/25 23:00 | Kentucky v South Carolina | L | 16-10 |
| NCAAF | 2021/09/18 23:00 | South Carolina v Georgia | L | 13-40 |
| NCAAF | 2021/09/11 16:00 | South Carolina v East Carolina | W | 20-17 |
| NCAAF | 2021/09/04 23:00 | Eastern Illinois v South Carolina | W | 0-46 |
| NCAAF | 2020/12/06 00:30 | South Carolina v Kentucky | L | 18-41 |
| NCAAF | 2020/11/29 00:30 | Georgia v South Carolina | L | 45-16 |
| NCAAF | 2020/11/22 00:30 | Missouri v South Carolina | L | 17-10 |
| NCAAF | 2020/11/15 00:30 | South Carolina v Mississippi | L | 42-59 |