Stadium: Gayle and Tom Benson Stadium Round: 1
Home Manager: Eric Morris Away Manager: Tim Rebowe
| NCAAF | 2021/03/27 16:00 | Incarnate Word v Nicholls State | W | 45-75 |
| NCAAF | 2019/11/02 21:00 | Nicholls State v Incarnate Word | W | 27-23 |
| NCAAF | 2018/10/27 20:00 | Nicholls State v Incarnate Word | W | 48-21 |
| NCAAF | 2017/10/28 19:00 | Incarnate Word v Nicholls State | W | 31-38 |
| NCAAF | 2021/10/09 17:00 | SE Louisiana v Nicholls State | L | 58-48 |
| NCAAF | 2021/10/02 20:00 | Houston Christian v Nicholls State | W | 17-48 |
| NCAAF | 2021/09/25 20:00 | North Alabama v Nicholls State | W | 14-31 |
| NCAAF | 2021/09/11 23:00 | Nicholls State v Lafayette | L | 24-27 |
| NCAAF | 2021/09/04 23:00 | Nicholls State v Memphis | L | 17-42 |
| NCAAF | 2021/04/10 20:00 | SE Louisiana v Nicholls State | L | 52-45 |
| NCAAF | 2021/04/03 17:00 | Nicholls State v McNeese State | L | 31-43 |
| NCAAF | 2021/03/27 16:00 | Incarnate Word v Nicholls State | W | 45-75 |
| NCAAF | 2021/10/02 23:00 | Incarnate Word v Northwestern State | W | 38-27 |
| NCAAF | 2021/09/25 16:00 | McNeese State v Incarnate Word | W | 0-31 |
| NCAAF | 2021/09/18 23:00 | Incarnate Word v Texas State | W | 42-34 |
| NCAAF | 2021/09/12 00:00 | Prairie View v Incarnate Word | W | 9-40 |
| NCAAF | 2021/09/02 23:00 | Incarnate Word v Youngstown State | L | 41-44 |
| NCAAF | 2021/04/17 16:00 | Sam Houston State v Incarnate Word | L | 42-14 |
| NCAAF | 2021/04/11 00:00 | Northwestern State v Incarnate Word | L | 49-47 |
| NCAAF | 2021/03/27 16:00 | Incarnate Word v Nicholls State | L | 45-75 |