[12] UL Lafayette 35-21 Troy [65] 2021-11-13 20:30
Stadium: Veterans Memorial Stadium Round: 1
Home Manager: Chip Lindsey Away Manager: Billy Napier
Head to Head
| NCAAF | 2019/11/23 22:00 | Troy v Lafayette | W | 3-53 |
| NCAAF | 2018/11/03 19:30 | Lafayette v Troy | L | 16-26 |
| NCAAF | 2015/12/05 22:00 | Lafayette v Troy | L | 17-41 |
| NCAAF | 2014/11/29 17:30 | Troy v Lafayette | W | 23-42 |
| NCAAF | 2012/09/08 12:00 | Troy v Lafayette | W | 24-37 |
| NCAAF | 2011/10/08 12:00 | Lafayette v Troy | W | 31-17 |
| NCAAF | 2010/10/16 12:00 | Troy v Lafayette | L | 31-24 |
| NCAAF | 2009/11/28 12:00 | Lafayette v Troy | L | 31-48 |
Home History
| NCAAF | 2021/11/13 17:30 | Colgate v Lafayette | L | 20-13 |
| NCAAF | 2021/11/06 16:30 | Lafayette v Holy Cross | L | 10-35 |
| NCAAF | 2021/11/04 23:30 | Georgia State v Lafayette | W | 17-21 |
| NCAAF | 2021/10/30 16:30 | Lafayette v Georgetown | W | 24-23 |
| NCAAF | 2021/10/30 16:00 | Texas State v Lafayette | W | 0-45 |
| NCAAF | 2021/10/21 23:30 | Lafayette v Arkansas State | W | 28-27 |
| NCAAF | 2021/10/16 17:00 | Lafayette v Harvard | L | 3-30 |
| NCAAF | 2021/10/12 23:30 | Appalachian St v Lafayette | W | 13-41 |
Away History
| NCAAF | 2021/11/06 19:30 | South Alabama v Troy | W | 24-31 |
| NCAAF | 2021/10/28 23:30 | Troy v Coastal Carolina | L | 28-35 |
| NCAAF | 2021/10/16 19:00 | Troy v Texas State | W | 31-28 |
| NCAAF | 2021/10/09 23:00 | Georgia Southern v Troy | W | 24-27 |
| NCAAF | 2021/10/02 19:30 | Troy v South Carolina | L | 14-23 |
| NCAAF | 2021/09/26 00:00 | Troy v UL Monroe | L | 16-29 |
| NCAAF | 2021/09/18 23:00 | Troy v Southern Mississippi | W | 21-9 |
| NCAAF | 2021/09/11 23:00 | Liberty v Troy | L | 21-13 |