Stadium: Roy Kidd Stadium Round: 1
Home Manager: Walt Wells Away Manager: Curt Mallory
| NCAAF | 2019/09/14 17:00 | Eastern Kentucky v Indiana State | W | 7-19 |
| NCAAF | 2014/11/29 18:00 | Eastern Kentucky v Indiana State | W | 16-36 |
| NCAAF | 2021/09/11 16:00 | Indiana State v Northwestern | L | 6-24 |
| NCAAF | 2021/08/28 22:00 | Eastern Illinois v Indiana State | W | 21-26 |
| NCAAF | 2019/11/23 20:00 | Indiana State v Missouri St | W | 51-24 |
| NCAAF | 2019/11/16 18:00 | Youngstown State v Indiana State | W | 17-24 |
| NCAAF | 2019/11/09 22:00 | Indiana State v Northern Iowa | L | 9-17 |
| NCAAF | 2019/11/02 17:00 | SO Illinois v Indiana State | L | 23-14 |
| NCAAF | 2019/10/26 19:00 | Indiana State v Illinois State | L | 7-24 |
| NCAAF | 2019/10/19 17:00 | South Dakota State v Indiana State | L | 42-23 |
| NCAAF | 2021/09/11 23:00 | Eastern Kentucky v Louisville | L | 3-30 |
| NCAAF | 2021/09/04 22:00 | Eastern Kentucky v Western Carolina | W | 31-28 |
| NCAAF | 2020/11/21 20:00 | Western Carolina v Eastern Kentucky | W | 17-49 |
| NCAAF | 2020/11/14 21:00 | Eastern Kentucky v Central Arkansas | L | 25-37 |
| NCAAF | 2020/11/07 20:00 | Stephen F. Austin v Eastern Kentucky | L | 24-6 |
| NCAAF | 2020/10/24 19:00 | Eastern Kentucky v Central Arkansas | W | 31-28 |
| NCAAF | 2020/10/17 19:30 | Eastern Kentucky v Troy | L | 29-31 |
| NCAAF | 2020/10/03 19:00 | Houston Christian v Eastern Kentucky | L | 33-30 |