[11] Toluca 3-1 Club America [2] 2021-04-25 22:30
Stadium: Estadio Nemesio Diez Round: 16
Referee: Oscar Macias Romo Home Manager: Hernan Cristante Away Manager: Santiago Hernan Solari Poggio
Head to Head
| Mexico - Liga MX | 2020/09/13 02:00 | Club America v Toluca | D | 1-1 |
| Europa - Vriendschappelijke wedstrijden | 2020/07/04 02:00 | Club America v Toluca | L | 2-0 |
| Mexico - Liga MX | 2019/08/11 17:00 | Toluca v Club America | L | 0-1 |
| Mexico - Liga MX | 2019/04/21 17:00 | Toluca v Club America | W | 3-2 |
| Mexico - Liga MX | 2018/12/03 00:30 | Club America v Toluca | L | 3-2 |
| Mexico - Liga MX | 2018/11/30 01:00 | Toluca v Club America | D | 2-2 |
| Mexico - Liga MX | 2018/11/04 01:00 | Club America v Toluca | D | 1-1 |
| Mexico - Liga MX | 2018/03/18 03:00 | Club America v Toluca | W | 1-2 |
Home History
| Mexico - Liga MX | 2021/04/19 00:00 | Santos Laguna v Toluca | L | 3-1 |
| Mexico - Liga MX | 2021/04/11 17:00 | Toluca v Monterrey | L | 1-2 |
| Mexico - Liga MX | 2021/04/05 02:05 | Leon v Toluca | L | 2-1 |
| Mexico - Liga MX | 2021/03/21 18:00 | Toluca v Puebla | D | 4-4 |
| Mexico - Liga MX | 2021/03/14 18:00 | Toluca v Pachuca | L | 0-2 |
| Mexico - Liga MX | 2021/03/06 01:30 | Atletico San Luis v Toluca | D | 0-0 |
| Mexico - Liga MX | 2021/03/03 01:00 | Tigres UANL v Toluca | W | 0-1 |
| Mexico - Liga MX | 2021/02/27 23:00 | Toluca v Atlas | D | 0-0 |
Away History
| Mexico - Liga MX | 2021/04/18 02:05 | Club America v Cruz Azul | D | 1-1 |
| CONCACAF Champions Cup | 2021/04/15 00:00 | Club America v CD Olimpia | L | 0-1 |
| Mexico - Liga MX | 2021/04/11 02:05 | Tigres UANL v Club America | W | 1-3 |
| CONCACAF Champions Cup | 2021/04/08 02:00 | CD Olimpia v Club America | W | 1-2 |
| Mexico - Liga MX | 2021/04/04 01:00 | Club America v Necaxa | W | 2-1 |
| Europa - Vriendschappelijke wedstrijden | 2021/03/27 23:30 | Club America v Monterrey | L | 0-2 |
| Mexico - Liga MX | 2021/03/20 03:00 | Mazatlan FC v Club America | W | 0-1 |
| Mexico - Liga MX | 2021/03/15 02:00 | Chivas Guadalajara v Club America | W | 0-3 |