Stadium: Fitton Field Round: 1
Home Manager: Bob Chesney Away Manager: John Garrett
| NCAAF FCS | 2018/11/03 16:30 | Holy Cross v Lafayette | L | 40-14 |
| NCAAF | 2017/09/30 17:05 | Holy Cross v Lafayette | W | 7-10 |
| NCAAF | 2019/11/08 00:30 | Lafayette v Coastal Carolina | W | 48-7 |
| NCAAF | 2019/11/02 21:00 | Texas State v Lafayette | W | 3-31 |
| NCAAF | 2019/11/02 16:30 | Fordham v Lafayette | W | 34-38 |
| NCAAF | 2019/10/26 19:30 | Bucknell v Lafayette | W | 17-21 |
| NCAAF | 2019/10/19 16:00 | Lafayette v Georgetown | L | 10-14 |
| NCAAF | 2019/10/17 23:30 | Lafayette v Arkansas State | W | 37-20 |
| NCAAF | 2019/10/11 23:00 | Lafayette v Princeton | L | 3-28 |
| NCAAF | 2019/10/10 00:00 | Appalachian St v Lafayette | L | 17-7 |
| NCAAF | 2019/11/02 16:30 | Holy Cross v Lehigh | W | 24-17 |
| NCAAF | 2019/10/26 17:00 | Colgate v Holy Cross | W | 10-31 |
| NCAAF | 2019/10/19 17:00 | Harvard v Holy Cross | L | 31-21 |
| NCAAF | 2019/10/12 16:30 | Holy Cross v Brown | W | 47-31 |
| NCAAF | 2019/10/05 18:00 | Holy Cross v Bucknell | W | 21-14 |
| NCAAF | 2019/09/28 16:00 | Holy Cross v Syracuse | L | 3-41 |
| NCAAF | 2019/09/21 17:00 | Holy Cross v Yale | L | 10-23 |
| NCAAF | 2019/09/07 17:00 | New Hampshire v Holy Cross | W | 10-13 |